Principal Scientist/Eng., Antibody Drug Conjugation - CDMO - NY

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Job description

Build out, design, and validate equipment for purification conjugation/manufacturing of Antibody Drug Conjugate suite. Guide and lead a team to ensure delivery of operational activities in related to manufacturing and development of Antibody Drug Conjugates.

Client Details

My client was newly founded in the United States in 2022 with the global parent company operating for the past decade. They have an established commercial scale state of the art cGMP biologics manufacturing facility servicing both large and small companies. Their United States facility is their main biologics location globally, with plans to build several more facilities internationally over the next decade.

Due to their rapid growth over the past 12 months and high demand for Antibody Drug Conjugation services, they are building out a brand new ADC manufacturing suite and development lab. My client plans to add several heads to their ADC group over the next 6 months.Their goal is to have the commercial scale ADC manufacturing plant up and running early 2025.

This role will report to the Associate Director, Manufacturing Technology and you will act as a lead for bio-conjugation/purification and tech transfer/scale up to manufacturing.

Description

• Lead the establishment of a state-of-the-art ADC lab, focusing on bio-conjugation, conjugation chemistry, process development, purification, and technology transfers.
• Help design the lab space in terms of purchasing equipment and tools needed for conjugation process
• Drive and execute strategies for ADC process development, optimizing bio-conjugation techniques, and purification processes to ensure the highest product quality and yield.
• Collaborate with cross-functional teams to ensure seamless tech transfer from development to manufacturing, while adhering to regulatory requirements and industry best practices.
• Contribute to tech transfer process to manufacturing group
• Provide technical expertise, guidance, and mentorship to junior team members, fostering an environment of continuous learning and growth.
• Act as a key liaison with clients, supporting technical discussions and contributing to the successful execution of ADC manufacturing projects.

Profile

• M.S./PhD in Chemistry, Biochemistry, Chemical Engineering, or related scientific disciplines with a minimum of 5 years of experience in the biopharmaceutical industry, preferably in ADCs.
• Proven expertise in bio-conjugation, conjugation chemistry, and purification processes related to ADC development and manufacturing.
• Extensive experience in establishing and optimizing processes for ADC manufacturing, tech transfers, and scale-up activities.
• Strong knowledge of regulatory requirements governing ADC development and manufacturing, including GMP guidelines.
• Excellent leadership and communication skills with the ability to work collaboratively in a multidisciplinary team environment.

Job Offer

• Competitive base salary
• Act as lead of Purification/Bio-conjugation ADC group
• Opportunity to grow and build out ADC function
• On-site position in Central New York
• State of the art manufacturing facility
• Excellent benefits package
• Report to the Associate Director, Manufacturing Technology
• Relocation package offered
• Pivotal role for company's aggressive expansion
• Amazing career growth opportunities

MPI does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, marital status, or based on an individual's status in any group or class protected by applicable federal, state or local law. MPI encourages applications from minorities, women, the disabled, protected veterans and all other qualified applicants.

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