Senior Scientist, Small Molecule Analytical Sciences

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Job description

Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . on Twitter , Facebook , Instagram , YouTube and LinkedIn .

Job Description
Technology and Therapeutic Platforms has an exciting opportunity for a Senior Scientist to join the Small Molecule Analytical Sciences (SMAS) team at AbbVie. The SMAS team is a global organization that provides enabling technologies to support Discovery Medicinal Chemistry initiatives. The scientist will join the Analytical and Purification Sciences group to execute compound purification on milligram to gram scale using preparative HPLC/SFC and devise innovative solutions to complex analytical and separation problems through the implementation of sophisticated instrumentation. The candidate will act as a lead scientist in his/her area of expertise on one or more projects, and critically evaluate relevant scientific advances and integrate this knowledge into research programs.

Key Responsibilities

• Execute compound purification on milligram to gram scale using preparative HPLC and SFC, to support small molecule drug discovery projects.
• Collaborate with medicinal chemistry teams through developing methods and providing technical guidance to solve analytical and purification problems.
• Collaborate within Analytical and Purification Sciences group to develop efficient workflows for sample prioritization and client communication.
• Proactively mentor colleagues in technical development and in establishing positive and productive working relationships.
• Maintain analytical and preparative HPLC and SFC instrumentation and independently troubleshoot instrument problems.
• Maintain a high level of productivity in the laboratory setting.
• May supervise one or more direct reports.
• Keep abreast of current literature and industry trends to assess new approaches in high-throughput purification and analytical technologies. Propose and implement new initiatives/directions for the team.
• Maintain a highly productive purification workflow, establish strategies that effectively optimize available equipment and personnel, and promote efficiency and enable new paradigms in Medicinal Chemistry.
• Demonstrate a high degree of responsibility in maintaining scientific standards and safe laboratory practices.
• Keep accurate and current records of research and/or project related activities according to AbbVie policies.

Qualifications
Qualifications

Position will be hired based on level of experience.
Senior Scientist I or Senior Scientist II.

• PhD or MS in Organic Chemistry, Analytical Chemistry, or related fields with 0-4+years (PhD); 8-10+ years (MS); or10-12+ years (BS) of postdoctoral and/or pharmaceutical industry experience.
• Hands-on experience with analytical and preparative scale HPLC and SFC
• Ability to operate and troubleshoot a variety of analytical and preparative instrumentation hardware and software.
• Knowledge of synthetic organic chemistry and the ability to communicate effectively with medicinal chemistry teams.
• Demonstrated record of achievement in chiral/achiral purification on milligram to gram scale for a variety of programs using multiple approaches and technologies.
• Proven effective written and verbal communication skills and ability to interact with scientists and engineers.

Preferred

• Experience of working in a fast-paced purification group and communicating effectively with Medicinal Chemistry teams.
• Experience in reversed-phase separations using HPLC
• Experience in chiral separations using HPLC and SFC.
• Experience with instrument development, automation, and/or programming.

Key Leadership Competencies

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance
• Learns fast, grasps the "essence" and can change course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others, nurtures innovation and manages to reality

Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible to participate in our short-term incentiveprograms.
• This job may be eligible to participate in our long-term incentiveprograms

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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