Sr Principal Scientist/Global Biomarker Lead Oncology Clinical Biomarkers

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Job description

Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr Principal Scientist/Global Biomarker Lead Oncology Clinical Biomarkers

What you will do

Lets do this. Lets change the world. The Senior Principal Scientist at Amgen is a leading expert responsible for planning and executing biomarker research within oncology clinical studies. Their work, using advanced technologies and methodologies, helps in the translation and clinical development of the company's products.

In this vital role you will successfully partner with cross-functional stakeholders to drive clinical biomarker innovation for oncology clinical assets.

• Responsible for preparing clinical biomarker strategies, leading biomarker development, implementation, and execution for one or more programs
• Responsible for robust clinical biomarker plans to deliver patient stratification/selection, pharmacodynamics, mechanism of action and resistance evidence from clinical trial samples
• Responsible for biomarker elements in clinical protocols, biomarker analysis plans, regulatory submissions, investigator meetings, advisory boards and publications
• Build productive relationships with team members and functional groups for integrating an aligned and prioritized clinical biomarker evidence plan that addresses clinical objectives and translational research
• Partners with cross functional stakeholders including to drive biomarker innovation at product level
• Interprets and communicates key clinical biomarker findings to cross functional teams including Precision Medicine teams and leadership

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of industry experience in oncology clinical biomarker development

Or

Masters degree and 4 years of industry experience in oncology clinical biomarker development

Or

Bachelors degree and 6 years of industry experience in oncology clinical biomarker development

Or

Associates degree and 10 years of industry experience in oncology clinical biomarker development

Or

High school diploma / GED and 12 years of industry experience in oncology clinical biomarker development

Preferred Qualifications:

• Doctorate degree (PhD and/or MD) with 5+ years industry experience developing oncology biomarker strategies in a clinical development setting
• Experience developing and executing pharmacodynamic, predictive and exploratory biomarkers such as mechanisms of resistance with clinical trial samples
• Experience implementing a broad array of biomarker platforms and technologies to support oncology clinical programs
• Clinical development experience working with cross-functional teams conducting clinical trials
• Demonstrated ability to establish and implement biomarker studies and collaborations with academic laboratories/KOLs as well as CROs
• Knowledge of biomarker assay development and qualification, analysis of clinical samples, and leading biomarker assay outsourcing processes with external vendors and CROs
• Experience working effectively in a team environment with cross-cultural partners
• Strong written and verbal communication skills with experience drafting technical reports and biomarker publications, and interpreting and communicating biomarker results to cross-functional teams

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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