Associate Scientist- Protein Therapeutics

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Job description

Associate Scientist- Protein Therapeutics
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description

The Protein Engineering group is a specialized team within the Protein Therapeutics department that is responsible for the optimization and engineering of large molecule drug candidates. We seek a highly motivated Associate Scientist to contribute to the engineering of novel antibody binding domains, fusion proteins (e.g. cytokines), and multispecific formats using structure-based rational and/or computational design approaches, as well as contribute to the development of new methodologies for high-throughput cloning, expression, and functional screening. The successful candidate will support cross-functional project teams to develop novel biologics for clinical development.

Essential Duties and Job Functions:

In this laboratory-based role, the successful candidate will support efforts to optimize large molecule therapeutics. The candidate will implement structure-based design and molecular biology approaches to rapidly generate engineered large molecule therapeutics for diverse target classes. Additional job requirements:

• Enable rapid optimization of novel antibody design via humanization, structure-based rational design, computational design, and/or library-based approaches.
  
• Enable fast generation of antibodies and/or multispecifics by utilizing state-of-the-art molecular biology approaches.
  

• Maintain familiarity with scientific literature and independently design, execute, analyze, and interpret experiments.
  
• Effectively communicate and present project goals and experimental findings to diverse audiences.
  
• Organize and execute multiple projects in a collaborative team setting.
  
• Thrive in a fast paced, data-driven and scientifically rigorous environment.
  
• Maintain compliance with company policies and record keeping.
  

Knowledge, Experience and Skills:

Applicants must have a B.S./M.S. in molecular biology, biochemistry, structural biology or a related field, with a minimum of 5+ for B.S./ 3+ for M.S. years of relevant professional experience. An ideal candidate will have experience in most of the following areas:

• Proficiency using various molecular biology techniques, such as PCR fragment assembly, vector design, site-directed mutagenesis, Gibson assembly, and/or Golden gate cloning is required.
  
• Familiarity with Geneious Prime or similar molecular design software is required.
  
• Proficiency in antibody variable domain reformatting is required.
  
• Strong experience in antibody humanization and/or liability remediation is preferred.
  
• Familiarity with structure-based protein engineering (e.g. PyMOL, MOE, etc) and design is preferred.
  

Preferred Experience:

An ideal candidate will preferably have 7+ for B.S./ 5+ for M.S. years of industry experience.

The salary range for this position is: $124,015.00 - $160,490.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans .

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Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

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Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

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